Publications

Qin T, Bronner ME. Multifaceted roles of sonic hedgehog signaling in mammalian inner ear development. Dev Biol. 2025 Aug;524:97-104. doi: 10.1016/j.ydbio.2025.05.007. Epub 2025 May 9. PMID: 40349906; PMCID: PMC12146078.

Dhillon-Richardson RM, Haugan AK, Lyons LW, McKenna JK, Bronner ME, Martik ML. Reactivation of an embryonic cardiac neural crest transcriptional profile during zebrafish heart regeneration. Proc Natl Acad Sci U S A. 2025 Jun 24;122(25):e2423697122. doi: 10.1073/pnas.2423697122. Epub 2025 Jun 18. PMID: 40531881; PMCID: PMC12207451.

Edens BM, Lin J, Bronner ME. Ancient emergence of neuronal heterogeneity in the enteric nervous system of jawless vertebrates. Dev Biol. 2025 Apr;520:117-124. doi: 10.1016/j.ydbio.2024.12.020. Epub 2025 Jan 3. PMID: 39756495; PMCID: PMC11830548.

Urrutia HA, Bronner ME. From neural crest migration to the onset of gangliogenesis. Curr Top Dev Biol. 2025;164:67-108. doi: 10.1016/bs.ctdb.2025.02.003. Epub 2025 Mar 13. PMID: 40571340.

Edens BM, Bronner ME. Making sense of vertebrate senses from a neural crest and cranial placode evo-devo perspective. Trends Neurosci. 2025 Mar;48(3):213-226. doi: 10.1016/j.tins.2024.12.008. Epub 2025 Jan 23. PMID: 39848838; PMCID: PMC11903184.

Solovieva T, Bronner ME. Congenital heart defects differ following left versus right avian cardiac neural crest ablation. Dev Biol. 2025 Mar;519:30-37. doi: 10.1016/j.ydbio.2024.12.003. Epub 2024 Dec 10. PMID: 39667652; PMCID: PMC11768310.

Readhead C, Mahler S, Dong Z, Sato Y, Yang C, Bronner ME. Automated non-invasive laser speckle imaging of the chick heart rate and extraembryonic blood vessels and their response to Nifedipine and Amlodipine drugs. Dev Biol. 2025 Mar;519:46-54. doi: 10.1016/j.ydbio.2024.12.005. Epub 2024 Dec 13. PMID: 39675502; PMCID: PMC11750601.

Li C, Gehring J, Bronner ME. Spatiotemporal dynamics of the developing zebrafish enteric nervous system at the whole-organ level. Dev Cell. 2025 Feb 24;60(4):613-629.e6. doi: 10.1016/j.devcel.2024.11.006. Epub 2024 Dec 5. PMID: 39642879; PMCID: PMC11859770.

Stundl J, Bronner ME. Tempting fate: Neural crest induction along the body axis. Cells Dev. 2025 Feb 1:204000. doi: 10.1016/j.cdev.2025.204000. Epub ahead of print. PMID: 39894223.

Desingu Rajan AR, Huang Y, Stundl J, Chu K, Irodi A, Yang Z, Applegate BE, Bronner ME. Generation of a zebrafish neurofibromatosis model via inducible knockout of nf2a/b. Dis Model Mech. 2024 Dec 1;17(12):dmm050862. doi: 10.1242/dmm.050862. Epub 2024 Dec 4. PMID: 39415595; PMCID: PMC11646113.

Urrutia HA, Stundl J, Bronner ME. Tlx3 mediates neuronal differentiation and proper condensation of the developing trigeminal ganglion. Dev Biol. 2024 Nov;515:79-91. doi: 10.1016/j.ydbio.2024.07.005. Epub 2024 Jul 15. PMID: 39019425; PMCID: PMC11317220.

Tseropoulos G, Mehrotra P, Podder AK, Wilson E, Zhang Y, Wang J, Koontz A, Gao NP, Gunawan R, Liu S, Feltri LM, Bronner ME, Andreadis ST. Immobilized NRG1 Accelerates Neural Crest like Cell Differentiation Toward Functional Schwann Cells Through Sustained Erk1/2 Activation and YAP/TAZ Nuclear Translocation. Adv Sci (Weinh). 2024 Sep;11(33):e2402607. doi: 10.1002/advs.202402607. Epub 2024 Jul 1. PMID: 38952126; PMCID: PMC11633358.

Bernardi YE, Sanchez-Vasquez E, Márquez RB, Piacentino ML, Urrutia H, Rossi I, Alcântara Saraiva KL, Pereira-Neves A, Ramirez MI, Bronner ME, de Miguel N, Strobl-Mazzulla PH. miR-203 secreted in extracellular vesicles mediates the communication between neural crest and placode cells required for trigeminal ganglia formation. PLoS Biol. 2024 Jul 22;22(7):e3002074. doi: 10.1371/journal.pbio.3002074. PMID: 39038054; PMCID: PMC11293684.

Dong Z, Mahler S, Readhead C, Chen X, Dickson M, Bronner M, Yang C. Non-invasive laser speckle contrast imaging (LSCI) of extra-embryonic blood vessels in intact avian eggs at early developmental stages. Biomed Opt Express. 2024 Jul 9;15(8):4605-4624. doi: 10.1364/BOE.530366. PMID: 39346990; PMCID: PMC11427191.

Edens BM, Stundl J, Urrutia HA, Bronner ME. Neural crest origin of sympathetic neurons at the dawn of vertebrates. Nature. 2024 Apr 17. doi: 10.1038/s41586-024-07297-0. Epub ahead of print. PMID: 38632395.

Suzuki M, Okumura A, Chihara A, Shibata Y, Endo T, Teramoto M, Agata K, Bronner ME, Suzuki KT. Fgf10 mutant newts regenerate normal hindlimbs despite severe developmental defects. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2314911121. doi: 10.1073/pnas.2314911121. Epub 2024 Mar 5. PMID: 38442169; PMCID: PMC10945807.

Bedois AMH, Parker HJ, Price AJ, Morrison JA, Bronner ME, Krumlauf R. Sea lamprey enlightens the origin of the coupling of retinoic acid signaling to vertebrate hindbrain segmentation. Nat Commun. 2024 Feb 20;15(1):1538. doi: 10.1038/s41467-024-45911-x. PMID: 38378737; PMCID: PMC10879103.

Edens BM, Bronner ME. Making developmental sense of the senses, their origin and function. Curr Top Dev Biol. 2024;159:132-167. doi: 10.1016/bs.ctdb.2024.01.015. Epub 2024 Feb 12. PMID: 38729675.

Tan FH, Bronner ME. Regenerative loss in the animal kingdom as viewed from the mouse digit tip and heart. Dev Biol. 2023 Dec 24;507:44-63. doi: 10.1016/j.ydbio.2023.12.008. Epub ahead of print. PMID: 38145727.

Piacentino ML, Fasse AJ, Camacho-Avila A, Grabylnikov I, Bronner ME. SMPD3 expression is spatially regulated in the developing embryo by SOXE factors. Dev Biol. 2023 Dec 3;506:31-41. doi: 10.1016/j.ydbio.2023.11.011. Epub ahead of print. PMID: 38052296.

Jacobs-Li J, Tang W, Li C, Bronner ME. Single-cell profiling coupled with lineage analysis reveals vagal and sacral neural crest contributions to the developing enteric nervous system. Elife. 2023 Oct 25;12:e79156. doi: 10.7554/eLife.79156. PMID: 37877560; PMCID: PMC10627514.

Lamanna F, Hervas-Sotomayor F, Oel AP, Jandzik D, Sobrido-Cameán D, Santos-Durán GN, Martik ML, Stundl J, Green SA, Brüning T, Mößinger K, Schmidt J, Schneider C, Sepp M, Murat F, Smith JJ, Bronner ME, Rodicio MC, Barreiro-Iglesias A, Medeiros DM, Arendt D, Kaessmann H. Publisher Correction: A lamprey neural cell type atlas illuminates the origins of the vertebrate brain. Nat Ecol Evol. 2023 Oct;7(10):1741. doi: 10.1038/s41559-023-02227-1. Erratum for: Nat Ecol Evol. 2023 Oct;7(10):1714-1728. PMID: 37749404; PMCID: PMC10555831.

Lamanna F, Hervas-Sotomayor F, Oel AP, Jandzik D, Sobrido-Cameán D, Santos-Durán GN, Martik ML, Stundl J, Green SA, Brüning T, Mößinger K, Schmidt J, Schneider C, Sepp M, Murat F, Smith JJ, Bronner ME, Rodicio MC, Barreiro-Iglesias A, Medeiros DM, Arendt D, Kaessmann H. A lamprey neural cell type atlas illuminates the origins of the vertebrate brain. Nat Ecol Evol. 2023 Oct;7(10):1714-1728. doi: 10.1038/s41559-023-02170-1. Epub 2023 Sep 14. Erratum in: Nat Ecol Evol. 2023 Sep 25;: PMID: 37710042; PMCID: PMC10555824.

Bedois AMH, Parker HJ, Bronner ME, Krumlauf R. Sea lamprey enlightens the origin of the coupling of retinoic acid signaling to vertebrate hindbrain segmentation. bioRxiv [Preprint]. 2023 Jul 7:2023.07.07.548143. doi: 10.1101/2023.07.07.548143. PMID: 37461675; PMCID: PMC10350081.

Stundl J, Martik ML, Chen D, Raja DA, Franěk R, Pospisilova A, Pšenička M, Metscher BD, Braasch I, Haitina T, Cerny R, Ahlberg PE, Bronner ME. Ancient vertebrate dermal armor evolved from trunk neural crest. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2221120120. doi: 10.1073/pnas.2221120120. Epub 2023 Jul 17. PMID: 37459514; PMCID: PMC10372632.

Tzung KW, Lalonde RL, Prummel KD, Mahabaleshwar H, Moran HR, Stundl J, Cass AN, Le Y, Lea R, Dorey K, Tomecka MJ, Zhang C, Brombacher EC, White WT, Roehl HH, Tulenko FJ, Winkler C, Currie PD, Amaya E, Davis MC, Bronner ME, Mosimann C, Carney TJ. A median fin derived from the lateral plate mesoderm and the origin of paired fins. Nature. 2023 Jun;618(7965):543-549. doi: 10.1038/s41586-023-06100-w. Epub 2023 May 24. PMID: 37225983; PMCID: PMC10266977.

Marable SS, Bronner ME. Reprogramming of trunk neural crest to a cranial crest-like identity alters their transcriptome and developmental potential. Differentiation. 2023 May-Jun;131:27-37. doi: 10.1016/j.diff.2023.04.001. Epub 2023 Apr 5. PMID: 37058884; PMCID: PMC10330191.

Bernardi YE, Sanchez-Vasquez E, Piacentino ML, Urrutia H, Rossi I, Saraiva KLA, Pereira-Neves A, Ramirez MI, Bronner ME, de Miguel N, Strobl-Mazzulla PH. Extracellular vesicle-localized miR-203 mediates neural crest-placode communication required for trigeminal ganglia formation. bioRxiv [Preprint]. 2023 Mar 15:2023.03.14.532527. doi: 10.1101/2023.03.14.532527. PMID: 36993487; PMCID: PMC10055076.

Koontz A, Urrutia HA, Bronner ME. Making a head: Neural crest and ectodermal placodes in cranial sensory development. Semin Cell Dev Biol. 2023 Mar 30;138:15-27. doi: 10.1016/j.semcdb.2022.06.009. Epub 2022 Jun 25. PMID: 35760729.

Mehrotra P, Ikhapoh I, Lei P, Tseropoulos G, Zhang Y, Wang J, Liu S, Bronner ME, Andreadis ST. Wnt/BMP Mediated Metabolic Reprogramming Preserves Multipotency of Neural Crest-Like Stem Cells. Stem Cells. 2023 Mar 17;41(3):287-305. doi: 10.1093/stmcls/sxad001. PMID: 36617947; PMCID: PMC10020983.

Bronner M. In the Spotlight-Established researcher. J Exp Zool B Mol Dev Evol. 2023 Jan 29. doi: 10.1002/jez.b.23190. Epub ahead of print. PMID: 36710471.

Piacentino ML, Hutchins EJ, Andrews CJ, Bronner ME. Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition. Proc Natl Acad Sci U S A. 2022 Dec 20;119(51):e2212879119. doi: 10.1073/pnas.2212879119. Epub 2022 Dec 12. PMID: 36508654; PMCID: PMC9907157.

Koontz A, Urrutia HA, Bronner ME. Retroviral lineage analysis reveals dual contribution from ectodermal placodes and neural crest cells to avian olfactory sensory and GnRH neurons. Nat Sci (Weinh). 2022 Jul;2(3):e20210037. doi: 10.1002/ntls.20210037. Epub 2022 May 25. PMID: 36311264; PMCID: PMC9605686.

Hutchins EJ, Gandhi S, Chacon J, Piacentino M, Bronner ME. RNA-binding protein Elavl1/HuR is required for maintenance of cranial neural crest specification. Elife. 2022 Oct 3;11:e63600. doi: 10.7554/eLife.63600. PMID: 36189921; PMCID: PMC9529247.

Zhang H, Shang R, Kim K, Zheng W, Johnson CJ, Sun L, Niu X, Liu L, Zhou J, Liu L, Zhang Z, Uyeno TA, Pei J, Fissette SD, Green SA, Samudra SP, Wen J, Zhang J, Eggenschwiler JT, Menke DB, Bronner ME, Grishin NV, Li W, Ye K, Zhang Y, Stolfi A, Bi P. Evolution of a chordate-specific mechanism for myoblast fusion. Sci Adv. 2022 Sep 2;8(35):eadd2696. doi: 10.1126/sciadv.add2696. Epub 2022 Sep 2. PMID: 36054355.

Galton, R., Fejes-Toth, K., & Bronner, M. E. (2022). Co-option of the piRNA pathway to regulate neural crest specification. Science advances, 8(32), eabn1441. https://doi.org/10.1126/sciadv.abn1441

Lin, L., Pinto, A., Wang, L., Fukatsu, K., Yin, Y., Bamforth, S. D., Bronner, M. E., Evans, S. M., Nie, S., Anderson, R. H., Terskikh, A. V., & Grossfeld, P. D. (2022). ETS1 loss in mice impairs cardiac outflow tract septation via a cell migration defect autonomous to the neural crest. Human molecular genetics, 31(24), 4217–4227. https://doi.org/10.1093/hmg/ddac174

Kastriti, M. E., Faure, L., Von Ahsen, D., Bouderlique, T. G., Boström, J., Solovieva, T., Jackson, C., Bronner, M., Meijer, D., Hadjab, S., Lallemend, F., Erickson, A., Kaucka, M., Dyachuk, V., Perlmann, T., Lahti, L., Krivanek, J., Brunet, J. F., Fried, K., & Adameyko, I. (2022). Schwann cell precursors represent a neural crest-like state with biased multipotency. The EMBO journal, 41(17), e108780. https://doi.org/10.15252/embj.2021108780

Papadogiannis, V., Pennati, A., Parker, H. J., Rothbächer, U., Patthey, C., Bronner, M. E., & Shimeld, S. M. (2022). Hmx gene conservation identifies the origin of vertebrate cranial ganglia. Nature, 605(7911), 701–705. https://doi.org/10.1038/s41586-022-04742-w

Stundl, J., Soukup, V., Franěk, R., Pospisilova, A., Psutkova, V., Pšenička, M., Cerny, R., Bronner, M. E., Medeiros, D. M., & Jandzik, D. (2022). Efficient CRISPR Mutagenesis in Sturgeon Demonstrates Its Utility in Large, Slow-Maturing Vertebrates. Frontiers in cell and developmental biology, 10, 750833. https://doi.org/10.3389/fcell.2022.750833

Williams, R. M., Lukoseviciute, M., Sauka-Spengler, T., & Bronner, M. E. (2022). Single-cell atlas of early chick development reveals gradual segregation of neural crest lineage from the neural plate border during neurulation. eLife, 11, e74464. https://doi.org/10.7554/eLife.74464

El-Nachef, W. N., Hu, C., & Bronner, M. E. (2022). Whole gut imaging allows quantification of all enteric neurons in the adult zebrafish intestine. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society, 34(2), e14292. https://doi.org/10.1111/nmo.14292.

Gandhi, S., & Bronner, M. E. (2021). Seq Your Destiny: Neural Crest Fate Determination in the Genomic Era. Annual review of genetics, 55, 349–376. https://doi.org/10.1146/annurev-genet-071719-020954.

Martik, M. L., & Bronner, M. E. (2021). Riding the crest to get a head: neural crest evolution in vertebrates. Nature reviews. Neuroscience, 22(10), 616–626. https://doi.org/10.1038/s41583-021-00503-2.

Parker HJ, De Kumar B, Pushel I, Bronner ME, Krumlauf R. Analysis of lamprey meis genes reveals that conserved inputs from Hox, Meis and Pbx proteins control their expression in the hindbrain and neural tube. Dev Biol. 2021; 479:61-76.

Hutchins EJ, Bronner ME. A Spectrum of Cell States During the Epithelial-to-Mesenchymal Transition. Methods Mol Biol. 2021; 2179:3-6.

Piacentino ML, Hutchins EJ, Bronner ME. Essential function and targets of BMP signaling during midbrain neural crest delamination. Dev Biol. 2021 Jun 6;477:251-261. doi: 10.1016/j.ydbio.2021.06.003. Epub ahead of print. PMID: 34102166.

Solovieva T, Bronner M. Schwann cell precursors: Where they come from and where they go. Cells Dev. 2021 Jun;166:203686. doi: 10.1016/j.cdev.2021.203686. Epub 2021 May 3. PMID: 33994354.

Tang W, Li Y, Li A, Bronner ME. Clonal analysis and dynamic imaging identify multipotency of individual Gallus gallus caudal hindbrain neural crest cells toward cardiac and enteric fates. Nat Commun. 2021 Mar 25;12(1):1894. doi: 10.1038/s41467-021-22146-8. PMID: 33767165; PMCID: PMC7994390.

Gandhi S, Li Y, Tang W, Christensen JB, Urrutia HA, Vieceli FM, Piacentino ML, Bronner ME. A single-plasmid approach for genome editing coupled with long-term lineage analysis in chick embryos. Development. 2021 Apr 1;148(7):dev193565. doi: 10.1242/dev.193565. Epub 2021 Apr 15. PMID: 33688075; PMCID: PMC8077534.

Hutchins EJ, Piacentino ML, Bronner ME. Transcriptomic Identification of Draxin-Responsive Targets During Cranial Neural Crest EMT. Front Physiol. 2021 Feb 3;12:624037. doi: 10.3389/fphys.2021.624037. PMID: 33613313; PMCID: PMC7886793.

Stundl J, Bertucci PY, Lauri A, Arendt D, Bronner ME. Evolution of new cell types at the lateral neural border. Curr Top Dev Biol. 2021;141:173-205. doi: 10.1016/bs.ctdb.2020.11.005. Epub 2021 Feb 6. PMID: 33602488.